Dawei Wang

Hainan Provincial Center for Disease Control and Prevention, Haikou, 570206, Hainan, China
Author    Correspondence author
Journal of Mosquito Research, 2024, Vol. 14, No. 4   doi: 10.5376/jmr.2024.14.0021
Received: 03 Jun., 2024    Accepted: 14 Jul., 2024    Published: 21 Aug., 2024

This is an open access article published under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Wang D.W., 2024, Future directions in vaccine research for emerging mosquito-borne pathogens, Journal of Mosquito Research, 14(4): 215-225 (doi: 10.5376/jmr.2024.14.0021)

Mosquito-borne diseases continue to pose significant public health challenges, particularly in the development of effective vaccines against emerging pathogens. This study provides a comprehensive review of the historical background of mosquito-borne disease vaccine development, highlighting both the successes and failures that have shaped current approaches. It explores the identification and characterization of emerging pathogens, with a particular focus on the role of climate and environmental changes in their spread. Innovative approaches in vaccine research, including advances in genomics and proteomics technologies, mRNA vaccines, and multivalent vaccine platforms, are examined in depth. Additionally, this study discusses antigenic variability, vaccine delivery in resource-limited settings, and the ethical considerations surrounding public acceptance. Case studies on Zika, Chikungunya, and Dengue vaccines showcase ongoing efforts and their impact. Looking forward, this study explores the integration of artificial intelligence, personalized vaccination strategies, and the potential for cross-protective vaccines targeting multiple pathogens. This study emphasize the critical importance of global collaboration and data sharing in advancing vaccine research and ensuring preparedness against future mosquito-borne disease threats.

Mosquito-borne diseases; Vaccine development; Emerging pathogens; mRNA vaccines; Global collaboration